Selected publications


  • Computed tomography (CT) findings and the prognostic value of the Koret CT score in cats with traumatic brain injury. Ohad Mann, Dana Peery, Ronnie Bader Segev, Sigal Klainbart, Efrat Kelmer, Ariel Sobarzo, Vered Shub, Kira Rapoport, Merav H. Shamir and Orit Chai. Journal of Feline Medicine and Surgery; April 2021; 1-7.



  • Chai O, Mazaki-Tovi M, Klainbart S, Kelmer E, Shipov A and Shamir MH. (2020) Serum levels of neuron-specific enolase in dogs following traumatic brain injury.  J. Comp. Path. 2020, Vol. 179, 45-51.
  • Rapoport K, Mateo I, Peery D, Mazaki-Tovi M,  Klainbart S, Kelmer E,  Ruggeri  M, Shamir M.H and Chai O. (2020) The prognostic value of the Koret CT score in dogs following traumatic brain injury, The Veterinary Journal, Volume 266, 2020.



  • M. Ruggeri, A. Rojas, O. Chai, H. Purzyc , E. Hanael, K. Rapoport, I. Barnoon,L. Konstantin, G. Baneth and M. H. Shamir. (2019) Intraspinal Spirocercosis in Dogs Detection of Intraspinal Spirocerca lupi in Canine Cerebrospinal Fluid by Polymerase Chain Reaction. J. Comp Pathol. 2019 Jul;170:105-112. 
  • E. Hanael, R.Veksler A.Friedman, G.Bar-Klein, V. Senatorov , Daniela Kaufer, Lilach     Konstantin, Orit Chai, Dana Peery, Merav H. Shamir. Blood-brain barrier dysfunction in canine epileptic seizures detected by dynamic contrast-enhanced magnetic resonance imaging.   Epilepsia. 2019 May;60(5):1005-1016.
  • Dan Z Milikovsky, Jonathan Ofer, Vladimir V. Senatorov Jr., Aaron R Friedman, Ofer Prager,     Liron Sheintuch, Netta Elazari, Ronel Veksler, Daniel Zelig, Itai Weissberg, Guy Bar-Klein, Evyatar Swissa, Erez Hanael, Gal Ben-Arie, Osnat Schefenbauer, Lyna Kamintsky, Rotem Saar-Ashkenazy, Ilan Shelef, Merav H Shamir, Ilan Goldberg1 Amir Glik, Felix Benninger, Daniela Kaufer and Alon Friedman. (2019) Paroxysmal slow cortical activity in Alzheimer’s disease and epilepsy is associated with blood-brain barrier dysfunction. Sci Transl Med. 2019 Dec 4;11(521).
  • Bruchim Y, Aroch I, Nivy R, Baruch S, Abbas A, Frank I, Fishelson Y, Codner C, Horowitz M. Impacts of previous heatstroke history on physiological parameters eHSP72 and biomarkers of oxidative stress in military working dogs. Cell Stress Chaperones. 2019 Sep;24(5):937-946.



  •   J. Freundt-Revilla, F. Heinrich, A. Zoerner, F. Gesell, M. Beyerbach, M. Shamir, A.   Oevermann, W. Baumga»rtner and A. Tipold. (2018) The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis. PLOSONE. 2018 Feb 6;13(2):e0187197.
  • Orit Chai, Einat Yas, Ori Brenner, Lilach Konstantin, Merav H. Shamir. (2018) Clinical characteristics of Spirocerca lupi migration in the spinal cord. Vet. Parasitol. 2018 Apr 15;253:16-21.
  • Chai O, Harrosh T, Bdolah-Avram T, Mazaki-Tovi M, Shamir HM. Characteristics of and risk factors for intervertebral disk extrusions in Pekingese. J Am Vet Med Assoc. 2018 Apr 1;252(7):846-851.



  • Chai, O.  Peery, D., Bdolah-Abram, T, Moscovich, E. Kelmer, E.   Klainbart,  S.C Milgram, J. and Shamir, HM. (2017). Computerized tomography findings in dogs with head trauma and development of a novel prognostic CT-based scoring system. Am. J. Vet. Res. 2017 Sep;78(9):1085-1090.



  • Barnoon, I., Shamir, H.M., A roch, I.,  Bdola-Abram, T.,  Chai, O., (2016) Evaluation of combined mycophenolate mofetil and prednisone treatment for meningoencephalomyelitis of unknown etiology in dogs: 25 cases (2005-2011). J Vet Emerg Crit Care (San Antonio). 2016 Jan-Feb;26(1):116-24.



  • Chamisha Y, Aroch I , Kuzi S , Srugo I , Bdolah-Abram T,  Chai O, Christopher MM, Merbl Y, Rothwell K, Shamir HM. (2015) The prognostic value of cerebrospinal fluid characteristics in dogs without deep pain perception due to thoracolumbar disc herniation. Res Vet Sci. 2015 Jun; 100:189-96.



  • Saragusty, J.,   Nadler, R.,  Shavit-Meyrav, A .,  Yamaguchi,N., Bdolah-Abram, T.,  Gibeon  L., Shamir, H.M.  (2014).  Comparative Skull Analysis Suggests Species-  Specific Captivity-Related Malformation in Lions (Panthera leo). PLOS One, 2014 Apr 9;9(4):e94527.
  • Merbl, Y., Sommer,A., Chai.O.,  Aroch, I., Zimmerman,G.,  Friedman,A.,   Soreq, H.  and Shamir, H.M. (2014) Tumor necrosis factor-a and interleukon-6 concentrations  in Cerebro-Spinal Fluid of dogs following seizures J Vet Intern Med. 2014 Nov Dec;28(6):1775- 81.



  • Chai, O.,  Sommer, A., Zimmerman, G.,  Soreq, H., Friedman, A.,  Bdolah-Abram, T.,  Aroch, I., and Shamir, H.M. (2013). Acetylcholinesterase activity in the Cerebro-Spinal Fluid of Dogs with Seizures. Vet J;198:292-4.



  • Shamir, H.M., Rubin, G., Aizenberg, Z., Berkovitz, Z,. Reifen, R., Horowitz, I.,  Bdolah-Abram, T., and Aroch, I., (2012). Needle biopsy for hepatic vitamin A levels in lions (Panthera Leo).    J. Zoo Wildl. Med. 43:207-13.



  • Roth, J., Shtokman, J., Shamir, H.M., Nissan, M.,  Shchetinkov, L.,  Trejo, L.L., Rochkind, S., (2011). Regeneration of the transected rat sciatic nerve after suturing or adhesion with cyanoacrylate glue. J Neurosurg; 114: 245-252.
  • Srugo, I., Aroch, I., Christopher, M.M., Chai, O., Goralnik, L.,  Bdolah-Abram, T.,  Shamir, H.M. (2011). Association of cerebrospinal fluid analysis findings with clinical signs and outcome in acute non-ambulatory thoracolumbar disc disease in dogs. J Vet Intern Med. ;25:846-55.



  • Shamir, H.M., Ofri, R.,  Bor, A.,Brenner, O.,Reicher, S.,  Obolensky, A., Averbukh. E.,  Banin, E., Gootwine, E.,  (2010). A novel day blindness in sheep: epidemiological, behavioural, electrophysiological and histopathological studies. Vet J.;185:130-7.
  • Gross-Tsubery, R., Chai, O.,  Shilo, Y.,  Miara, L., Horowitz, I.H.,  Shmueli, A.,   Aizenberg, I.,  Hoffman, C.,  Reifen, R., Shamir, H.M. PI (2010). Computed tomographic analysis of calvarial hyperostosis in captive lions. Vet Radiol Ultrasound. ;51:34-8.
  • Aroch, I., Keidar, I., Himelstein, A., Schechter, M., Shamir, H.M.,   Segev, G., (2010). Diagnostic and prognostic value of serum creatine-kinase activity in ill cats: a retrospective study of 601 cases. J Feline Med Surg. ; 12:466-75.



  •  Chai O, Johnston DE, Shamir MH. Bite wounds involving the spine: characteristics, therapy and outcome in seven cases. Vet J. 2008 Feb;175(2):259-65.
  •  Shamir, H.M., Chai, O., Loeb, E., C (2008). A method for intervertebral space distraction before stabilization combined with complete ventral slot for treatment of disc-associated wobbler syndrome in dogs. Vet Surg. ;37:186-92.
  • Shamir, H.M., Horowitz, I., Chaffe,R. M., Grinberg, K., Bellaiche, M., and Elad,  D.,(2008). Botulism in four captive lion cubs; manifestations and environmental studies. Isr J Vet Med. 63:21-28.
  • Chai, O., Shelef, I., Brenner, O.,  Dogadkin, O.,  Aroch, I.,   Shamir, H.M.  (2008). Magnetic resonance imaging findings of spinal intramedullary spirocercosis. Vet Radiol Ultrasound. 49:456-459.



  • Dvir. E., Perl. S., Loeb, E., Shklar-Hirsch, S.,  Chai, O.,  Mazaki-Tovi,M., C Aroch, I., Shamir, H.M.,  (2007). Spinal intramedullary aberrant Spirocerca lupi migration in 3 dogs. J Vet Intern Med.; 21:860-4.